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Global Controlled Release Drug Delivery Market Opportunity & Clinical Trial Outlook 2025

November 2018 | 700 pages | ID: G8687E92826EN
Kuick Research

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'Global Controlled Release Drug Delivery Market Opportunity & Clinical Trial Outlook 2025' Report Highlights:
  • Development of Controlled Drug Delivery Technology
  • Approaches for Controlled Drug Delivery
  • Global Controlled Release Drug Clinical Pipeline by Phase, Indication, Drug Class
  • Global Controlled Release Drug Clinical Pipeline: 218 Drugs
  • Marketed Controlled Release Drugs: 118 Drugs
  • Majority Drugs In Phase-II & Phase-III Trials: More Than 80
  • Global Controlled Drug Delivery Market Future Outlook
Controlled drug delivery technology is the one of the most rapidly advancing area in human healthcare management and already had an enormous impact on medical technology with the potential to improve health. As the goal of any drug delivery system is to provide a therapeutic amount of drug to a proper site in the body so that the desired drug concentration can be achieved promptly and then maintained, all these characteristics are provided by controlled drug delivery technologies.

Controlled drug delivery systems provide uniform concentration of drug to the absorptions site and thus allow the maintenance of plasma concentration within the therapeutic range which minimizes not only the side effects but also the frequency of administration. The term controlled release has a meaning that goes beyond the scope of sustained drug action.

One of the major factors for the increased market tendencies for controlled drug delivery market is the improvement and advances in the use of varied approaches. Polymeric controlled drug delivery is the most applied strategy towards the controlled drug delivery. Polymers used for coating and in other forms consist of two forms synthetic and biodegradable polymers. The extensive usage of biodegradable polymers in medical devices is expected to push the global biodegradable polymers market.

The future of controlled drug delivery is quite fertile with respect to various upcoming systems and products which will be providing the controlled release mechanism. Some of the products have been launched and some will be coming soon as are under clinical investigations. Various depot systems are under construction, along with the approaches using nanoparticulate system, transdermal controlled deliveries and much more. Newer, more sophisticated, transdermal patches and other transdermal controlled drug delivery systems are being developed that are currently being tested in clinical trials.

KuicK Research report on the 'Controlled Release Drug Delivery Market' is a result of intensive study of the novel segment and its future market potential. The report has been made with key focus on the current market trends, superiority of Controlled Drug Delivery methods to traditional drug delivery methods. The report also provides key insights into the technology and approaches of controlled delivered drugs, recent developments and market dynamics that might impact its future. The report concludes with comprehensive insight on ongoing clinical trials of controlled delivered drugs and future trends which clearly highlights it as one of the most promising market in the modern drug delivery segment.
1. DRUG DELIVERY: AN ADVANCING TRAJECTORY

1.1 Preamble Towards Drug Delivery
1.2 Ideal Mode of Drug Delivery System

2. WHAT IS CONTROLLED DRUG DELIVERY?

2.1 Novel Drug Delivery Systems
2.2 Preamble to Controlled Drug Delivery

3. DEVELOPMENT OF CONTROLLED DRUG DELIVERY TECHNOLOGY

3.1 First Generation
3.2 Second Generation

4. BASICS OF CONTROLLED DRUG DELIVERY

4.1 Prerequisites of Controlled Delivery
4.2 Rationale for Controlled Drug Delivery

5. MECHANISM OF CONTROLLED DRUG RELEASE

5.1 Diffusion Controlled
5.2 Dissolution Controlled System
5.3 Water Penetration Controlled System
5.4 Erosion Controlled System
5.5 Ion-Exchange Controlled System

6. CATALOGING OF CONTROLLED DRUG DELIVERY

6.1 Classification Based Over Delivery Systems
6.2 Classification Based Over Technicality
6.3 Classification Based Over Routes

7. APPROACHES FOR CONTROLLED DRUG DELIVERY

7.1 Polymers
7.2 Chronopharmaceutics
7.3 Nanoparticulate Delivery System

8. GLOBAL CONTROLLED RELEASE DRUG CLINICAL PIPELINE OVERVIEW

8.1 Phase
8.2 Country/Region
8.3 Mode of Action
8.4 Drug class
8.5 Indication

9. APPLICATION OF CONTROLLED DRUG DELIVERY

9.1 Diabetes
9.2 Cancer
9.3 Cardiovascular Diseases
9.4 Neurological Disorders
9.5 Infections

10. DRUG DESIGNING FOR CONTROLLED DELIVERY

10.1 Enteral Dosage Formulations
  10.1.1 Solid Dosage Forms
  10.1.2 Liquid Dosage Forms
  10.1.3 Inhalation Dosage Forms
10.2 Parenteral Dosage Forms
  10.2.1 Injectable Dosage Forms
  10.2.2 Implantable Device
10.3 General Mechanisms of Drug Release

11. MARKET INCLINATIONS

11.1 Market over Routes of Administration
11.2 Market over Approaches

12. GLOBAL CONTROLLED DRUG DELIVERY MARKET DYNAMICS

12.1 Accelerative Parameters
12.2 Challenges

13. GLOBAL CONTROLLED DRUG DELIVERY MARKET FUTURE OUTLOOK

13.1 Ongoing Clinical Trials
13.2 Future Market Opportunities

14. GLOBAL CONTROLLED DRUG DELIVERY CLINICAL TRIALS BY COMPANY, INDICATION AND PHASE

14.1 Unknown
14.2 Research
14.3 Preclinical
14.4 Clinical
14.5 Phase-I
14.6 Phase-I/II
14.7 Phase-II
14.8 Phase-II/III
14.9 Phase-III
14.10 Preregistration
14.11 Registered

15. MARKETED CONTROLLED RELEASE DRUG CLINICAL INSIGHT BY COMPANY, INDICATION AND PHASE

16. COMPETITIVE LANDSCAPE

16.1 Allergan
16.2 Amylin Pharmaceuticals
16.3 AstraZeneca
16.4 BioAlliance Pharma
16.5 Biogen
16.6 Collegium Pharmaceutical
16.7 Controlled Therapeutics (Ferring Pharmaceuticals)
16.8 Cosmo Pharmaceuticals
16.9 Egalet
16.10 Elan Corporation
16.11 Encore Therapeutics
16.12 Flamel Technologies
16.13 GlaxoSmithKline
16.14 Heron Therapeutics
16.15 iCeutica
16.16 Mithra Pharmaceuticals
16.17 Neurim Pharmaceuticals
16.18 Novartis
16.19 Orexigen Therapeutics
16.20 Otsuka Pharmaceutical
16.21 Pfizer
16.22 Purdue Pharma
16.23 Syntex Pharmaceuticals International
16.24 Takeda
16.25 Zealand Pharma

LIST OF FIGURES

Figure 1-1: Characteristics of an Ideal Drug Delivery System
Figure 2-1: Limitations of the Conventional Drug Delivery Systems
Figure 2-2: Diversification of the Novel Drug Delivery Platforms
Figure 3-1: History of Drug Delivery Technology from First Generation till Third Generation
Figure 3-2: Barriers to be Overcome by the Third Generation Drug Delivery System
Figure 4-1: Demonstration of the Targeted & Non-Targeted Drug Delivery
Figure 4-2: Controlled Drug Release is by Zero Order Mechanism
Figure 5-1: Differentiation of the Two Forms of the Diffusion Controlled Mechanisms
Figure 5-2: Mechanism of Encapsulation Dissolution Controlled System
Figure 5-3: Osmotic Release of the Drug Delivery with the Controlled Mechanism
Figure 5-4: Illustration of Erosion Mechanisms Found in Matrix Systems
Figure 6-1: Plasma Concentration v/s Time Profile in Conventional & Controlled Release
Figure 6-2: Comparison of Varied Modified Drug Release Systems
Figure 6-3: Illustration of Mechanism of Pulsatile Drug Release in Pulsincap
Figure 6-4: Classification Based Over the Technicality Erudition
Figure 6-5: Structural Differentiation among Varied Classified Drug Delivery Systems
Figure 6-6: Classification Based over the Route of Administration
Figure 7-1: Categorization of Polymeric Controlled Drug Delivery Devices
Figure 7-2: Varied Nanostructures Available for the Nanoparticulate Delivery System
Figure 8-1: Global - Controlled Release Drug Clinical Pipeline by Phase (%), 2018 till 2025
Figure 8-2: Global - Controlled Release Drug Clinical Pipeline by Phase (Number), 2018 till 2025
Figure 8-3: Global - Controlled Release Drug Clinical Pipeline by Phase (%),2018 till 2025
Figure 8-4: Global - Controlled Release Drug Clinical Pipeline by Phase (Number), 2018 till 2025
Figure 8-5: Global - Controlled Release Drug Clinical Pipeline by Country/Region (Number),2018 till 2025
Figure 8-6: Global - Controlled Release Clinical Drug Pipeline by Mode of Action (Number), 2018 till 2025
Figure 8-7: Global - Controlled Release Drug Clinical Pipeline by Drug Class (Number), 2018 till 2025
Figure 8-8: Global - Controlled Release Drug Clinical Pipeline by indication (Number), 2018 till 2025
Figure 9-1: Major Non-Invasive Administrative Routes of Insulin Delivery
Figure 9-2: Layout of the Controlled Drug Delivery Approaches in Cancer Therapeutics
Figure 9-3: Controlled Drug Delivery Approaches used to Deliver Drugs to CNS
Figure 10-1: Dosage Formulations for the Controlled Drug Delivery
Figure 10-2: Mechanism of the Controlled Drug Release of the Solid Dosage Forms
Figure 10-3: Representation of Categories of Liquid Dosage Form
Figure 10-4: Mechanism of Controlled Delivery of Parenteral Dosage Forms
Figure 10-5: General Forms of Oral Controlled Release System Mechanism
Figure 10-6: Schematic Diffusion Controlled Drug Release from Inert Matrices
Figure 10-7: Demonstration of the Osmotic Pump Drug Release Mechanism
Figure 11-1: Drug Delivery Share by Route of Administration, 2016
Figure 11-2: Global - Oral Drug Delivery Administration Market (US$ Billion), 2017 & 2025
Figure 11-3: Global - Injectable Drug Delivery Systems Market (US$ Billion), 2017 & 2025
Figure 11-4: Global - Implantable Device Market (US$ Billion), 2017 & 2025
Figure 11-5: Global - Topical Drug Delivery System Market (US$ Billions), 2017 & 2025
Figure 11-6: Global - Biodegradable Polymer Market (US$ Billions), 2017 & 2025
Figure 11-7: Global - Smart Polymers Market (US$ Billion), 2017 & 2025
Figure 11-8: Global - Nanomedicine Market (US$ Billion), 2017 - 2025
Figure 12-1: Accelerative Parameters of Controlled Drug Delivery Systems
Figure 12-2: Major Challenges Faced by Controlled Drug Delivery System
Figure 13-1: Illustration of Clinical Trials in Varied Segments for Controlled Drug Delivery


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